Euphorion of Chalcis was a Hellenistic poet and scholar active in the mid-3rd century BCE. His career was spent in the service of powerful patrons, first as librarian for Alexander, tyrant of Corinth, and later as head of the public library in Antioch under King Antiochus the Great. These positions place him within the courtly and intellectual networks of the Hellenistic successor kingdoms.

His extensive output survives only in fragments. A prolific writer of learned hexameter verse, his known works include Chiliades, Hesiod, and Mopsopia. His poetry was characterized by obscure mythological references, rare words, and a dense, erudite style designed for a highly educated audience.

Euphorion was a major figure in Hellenistic poetry, renowned for his difficult and allusive style. He became a model for later poets like Parthenius of Nicaea and influenced Roman neoterics such as Cinna and Catullus. His work exemplifies the period's fusion of poetic creativity with philological scholarship, and his influence persisted into the Roman era.