Colluthus of Lycopolis was a Greek epic poet from Lycopolis in Egypt, active during the late 5th or early 6th century CE under the reign of Emperor Anastasius I. The sole biographical notice comes from the Suda, which confirms his origin and era but provides no further details on his life or education.

His only surviving work is the Abduction of Helen, a short epic poem of 392 hexameters that recounts the Judgement of Paris and Helen's kidnapping. The Suda also credits him with several lost works, including the Calydoniaca, Persica, and Encomia, though no fragments of these texts remain.

Colluthus exemplifies late antique Greek epic poetry, producing learned, Homeric-style narratives on mythological themes. The Abduction of Helen survives in a 13th-century manuscript alongside other epic cycle poems. It stands as a minor but typical product of the literary culture in the late Roman Egyptian chora, where Homeric imitation retained both pedagogical and aesthetic value.